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Modifiers of estrogen metabolism
Changing the ratio of estrone metabolites
:
Indole-3-Carbinol (found in cruciferous vegetables) promotes C-2 over C-16. See
Indole-3-Carbinol Induces Bad to Good Estrogen
.
Diindolylmethane (DIM) the result of stomach acid's action on I3C, and probably the most active metabolite in I3C. For people in whom IC3 causes GI upset, DIM may be more absorbable.
"Most common dosing is 60mg DIM twice a day for women and 90-120mg/day for men." (
Natural Approaches to Estrogen Metabolism for Women and Men
)
Products:
Indolplex
(Tyler)
BioDIM
(Vitamin Research Products)
Products containing it, for bodybuilding
More info
I3C/DIM
, which contains two articles from the
RRP Newsletter
(about recurrent respiratory papilloma). Includes info about where to buy both.
Controversy
about the relative benefits of IC3 and DIM.
Last updated 28 October 2007